Article

Multi-modal quantification of pathway activity with MAYA

2022-07-20

Abstract excerpt

Signaling pathways can be activated through various cascades of genes depending on cell identity and biological context. Single-cell atlases now provide the opportunity to inspect such complexity in health and disease. Yet, existing reference tools for pathway scoring resume activity of each pathway to one unique common metric across cell types. Here, we present MAYA a computational method that enables the automat...

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Literature Corpus work: faceb3f1-6250-56d3-8df4-659f6a0dfc9c
DOI: 10.1101/2022.07.19.500633

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