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scTPA: a web tool for single-cell transcriptome analysis of pathway activation signatures

15 May 2020

Abstract excerpt

MOTIVATION: At present, a fundamental challenge in single-cell RNA-sequencing data analysis is functional interpretation and annotation of cell clusters. Biological pathways in distinct cell types have different activation patterns, which facilitates the understanding of cell functions using single-cell transcriptomics. However, no effective web tool has been implemented for single-cell transcriptome data...

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PMID: 32437538
DOI: 10.1093/bioinformatics/btaa532

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