Article
A geometric approach to characterize the functional identity of single cells.
Nature communications - 17 Apr 2018
Mohammadi Shahin, Ravindra Vikram, Gleich David F, Grama Ananth
Abstract excerpt
Single-cell transcriptomic data has the potential to radically redefine our view of cell-type identity. Cells that were previously believed to be homogeneous are now clearly distinguishable in terms of their expression phenotype. Methods for automatically characterizing the functional identity of cells, and their associated properties, can be used to uncover processes involved in lineage differentiation as well...
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