Back to search

Article

High order expression dependencies finely resolve cryptic states and subtypes in single cell data

2023-12-18

Abstract excerpt

<h4> A bstract </h4> Single cells are typically typed by clustering in reduced dimensional transcriptome space. Here we introduce Stator, a novel method, workflow and app that reveals cell types, subtypes and states without relying on local proximity of cells in gene expression space. Rather, Stator derives higher-order gene expression dependencies from a sparse gene-by-cell expression matrix. From these depend...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1b5a4586-33a6-5628-a901-8387696e1e1a
DOI
10.1101/2023.12.18.572232
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
High order expression dependencies finely resolve cryptic states and subtypes in single cell dataDOI 10.1101/2023.12.18.572232
Select a neighboring publication to make it the new centre.