Article

Artificial intelligence and omics-based autoantibody profiling highlights autoimmunity targeting ligand-receptor interaction in dementia

2024-09-23

Abstract excerpt

Dementia is a neurodegenerative syndrome marked by the accumulation of disease-specific proteins and immune dysregulation, including autoimmune mechanisms involving autoantibodies. Current diagnostic methods are often invasive, time-consuming, or costly. This study explores the use of proteome-wide autoantibody screening (PWAS) for noninvasive dementia diagnosis by analyzing serum samples from Alzheimer’s disease...

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Literature Corpus work: c9806d75-cda8-55cf-97b0-0cf91a2c0dd1
DOI: 10.1101/2024.09.20.24313547

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