Article

The evolution of the matrix genes of human influenza A and relationships to functional properties

2001-01-01

Abstract excerpt

Amantadine and rimantadine are anti-influenza A drugs that target the M2 protein, located within the viral envelope. Over the last century, the circulating human Influenza A viruses in the UK have included H1N1, H2N2 and H3N2 antigenic subtypes. The main aim of this study was to analyse the national archive of influenza A viruses for amantadine susceptibility as there is limited data on natural resistance over the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fa23056a-26f0-5290-a9e7-aa1df5f969f4
DOI: 10.21954/ou.ro.0000fcf9

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The evolution of the matrix genes of human influenza A and relationships to functional propertiesDOI 10.21954/ou.ro.0000fcf9Read

The matrix gene of influenza A H5N1 in Egypt, 2006-2016: molecular insights and distribution of amantadine-resistant variants.Semantic proximity Read

Re-emergence of amantadine-resistant variants among highly pathogenic avian influenza H5N1 viruses in Egypt.Semantic proximity Read

Investigating the Molecular Basis of Antiviral Resistance in the Perspective of Influenza A VirusSemantic proximity Read

Influenza virus genetics.Semantic proximity Read

Large-Scale Sequence Analysis of M Gene of Influenza A Viruses from Different Species: Mechanisms for Emergence and Spread of Amantadine ResistanceSemantic proximity Read

The genesis and spread of reassortment human influenza A/H3N2 viruses conferring adamantane resistance.Semantic proximity Read

Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005.Semantic proximity Read

Amantadine resistance in relation to the evolution of influenza A(H3N2) viruses in Iran.Semantic proximity Read

Adamantane-resistant influenza a viruses in the world (1902-2013): frequency and distribution of M2 gene mutations.Semantic proximity Read

Genomic events underlying the changes in adamantane resistance among influenza A(H3N2) viruses during 2006-2008.Semantic proximity Read

Evolution of Influenza Viruses—Drug Resistance, Treatment Options, and ProspectsSemantic proximity Read

The emergence of adamantane resistance in influenza A(H1) viruses in Australia and regionally in 2006.Semantic proximity Read