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The matrix gene of influenza A H5N1 in Egypt, 2006-2016: molecular insights and distribution of amantadine-resistant variants.

Virus genes - 1 Dec 2016

Naguib Mahmoud M, Hagag Naglaa, El-Sanousi Ahmed A, Hussein Hussein Ali, Arafa Abdel-Satar

Abstract excerpt

Large-scale sequence analysis of Matrix (M) gene and its coding proteins M1 and M2 was performed for 274 highly pathogenic avian influenza viruses H5N1 circulated in Egypt from 2006 to 2016. The aim is to study the amantadine-resistant markers distribution and to estimate the evolutionary rate. 246 viruses were obtained from the Global Initiative on Sharing All Influenza Data base, and 28 additional viruses were...

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PMID: 27448682
DOI: 10.1007/s11262-016-1373-3

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MCC

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