Article
Re-emergence of amantadine-resistant variants among highly pathogenic avian influenza H5N1 viruses in Egypt.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2016
El-Shesheny Rabeh, Bagato Ola, Kandeil Ahmed, Mostafa Ahmed, Mahmoud Sara H, Hassanneen Hamdi M, Webby Richard J, Ali Mohamed A, Kayali Ghazi
Abstract excerpt
Highly pathogenic avian influenza (HPAI) H5N1 virus continues to undergo substantial evolution. Emergence of antiviral resistance among H5N1 avian influenza viruses is a major challenge in the control of pandemic influenza. Numerous studies have focused on the genetic and evolutionary dynamics of the hemagglutinin and neuraminidase genes; however, studies on the susceptibility of HPAI H5N1 viruses to amantadine...
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