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Article

Amantadine resistance in relation to the evolution of influenza A(H3N2) viruses in Iran.

Antiviral research - 1 Nov 2010

Yavarian Jila, Azad Talat Mokhtari, Zheng Xiang, Gregory Victoria, Lin Yi Pu, Hay Alan

Abstract excerpt

The aminoadamantanes, amantadine and rimantadine, have been used to prevent and treat influenza A virus infections for many years. Several reports have shown an increased level of resistance to these drugs, particularly among influenza A(H3N2) subtype viruses, during recent years. We observed an increase in amantadine resistance, due to a Ser31Asn mutation in the M2 channel protein, among A(H3N2) viruses...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20816700
DOI: 10.1016/j.antiviral.2010.08.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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