Article

Predicting targeted- and immunotherapeutic response outcomes in melanoma with single-cell Raman spectroscopy and AI

2025-05-21

Abstract excerpt

<h4>PURPOSE</h4> Identifying reliable predictors of immunotherapeutic response in melanoma remains an outstanding challenge. Existing transcriptomic and proteomic profiling methods for the tumor-immune microenvironment (TIME) are costly and may not faithfully capture modifications actively impacting tumor behavior. Here, we present a non-destructive, single-cell approach combining Raman spectroscopy and machine l...

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Literature Corpus work: fa0e8b57-fa6e-54be-b54e-40bd7ffb8494
DOI: 10.1101/2025.05.16.654612

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