Article

De novo single-cell biological analysis of drug resistance in human melanoma through a novel deep learning-powered approach

2025-08-22

Abstract excerpt

Elucidating drug response mechanisms in human melanoma is crucial for improving treatment outcomes. Although scRNA-seq captures gene expression at the individual cell level, existing tools to gain deeper insights into a studied population pertaining to melanoma drug resistance are far from perfect. Therefore, we propose a deep learning (DL)-based approach to unveil molecular mechanisms underlying melanoma drug res...

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Literature Corpus work: 03e869e3-ef53-50a1-a1a8-1380e87ba5ef
DOI: 10.1101/2025.08.18.670074

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