Article

<i>Ex vivo</i> expansion of skeletal muscle stem cells with a novel small compound inhibitor of eIF2α dephosphorylation

2019-03-04

Abstract excerpt

<h4>BACKGROUND</h4> Regeneration of adult tissues requires the activity of rare, mitotically quiescent somatic stem cells. These features are illustrated by the muscle stem cell (MuSC), also known as the satellite cell for its satellite position underneath the basal lamina of the myofiber. Isolation of MuSCs results in their rapid activation of the myogenic program and their subsequent culture ex vivo leads to lo...

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Literature Corpus work: f9efc15c-2de7-5433-b3f7-6e9713700181
DOI: 10.1101/567461

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