Article
Isolation of Skeletal Muscle Stem Cells for Phenotypic Screens for Modulators of Proliferation.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Hinken Aaron C, Billin Andrew N
Abstract excerpt
Adult skeletal muscle contains a population of resident stem cells known as muscle stem cells (MuSC) or satellite cells. This population of cells is required for regeneration of functional myofibers after damage. Aging reduces the proliferative response of satellite cells post-injury. This deficient response is thought to contribute to slowed recovery of muscle function after damage in the elderly and may also...
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