Article

Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSCs-derived myogenic progenitor cells

2024-12-10

Abstract excerpt

<h4>Summary</h4> Generation of in vitro induced pluripotent cells (hiPSCs)-derived skeletal muscle progenitor cells (SMPCs) holds great promise for regenerative medicine for skeletal muscle wasting diseases, as for example Duchenne Muscular Dystrophy (DMD). Multiple approaches, involving ectopic expression of key regulatory myogenic genes or small molecules cocktails, have been described by different groups to o...

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Literature Corpus work: 7e8f4e07-cbfb-5c3a-9f43-50e1a60aeb6d
DOI: 10.1101/2024.12.09.624203

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