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Abrogation of group III phospholipase A2 inhibits tumor growth and metastasis in ovarian cancer and promotes chemo-sensitization

2021-01-19

Abstract excerpt

<h4>Background: </h4> Aberrant lipogenicity and deregulated autophagy are common in most advanced human cancer and therapeutic strategies to exploit these pathways are currently under consideration. Group III Phospholipase A2 (sPLA2-III/PLA2G3), an atypical secretory PLA2, is recognized as a regulator of lipid metabolism associated with oncogenesis. Though recent studies reveal that high PLA2G3 expression signific...

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Literature Corpus work
f9e1bdc4-cc9f-597c-92ee-af15a4943a30
DOI
10.21203/rs.3.rs-147840/v1
Open publication

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Abrogation of group III phospholipase A2 inhibits tumor growth and metastasis in ovarian cancer and promotes chemo-sensitizationDOI 10.21203/rs.3.rs-147840/v1
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