Article

A database of simulated tumor genomes towards accurate detection of somatic small variants in cancer

2018-02-07

Abstract excerpt

<h4>Background</h4> Somatic mutations promote the transformation of normal cells to cancer. Accurate identification of such mutations facilitates cancer diagnosis and treatment. A number of callers have been developed to predict them from paired tumor/normal or unpaired tumor sequencing data. However, the small size of currently available experimentally validated somatic sites limits evaluation and then improveme...

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Literature Corpus work: f9ab6b9c-c66a-51f5-b501-9e12e8e05d48
DOI: 10.1101/261503

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