Article

Standard operating procedure for somatic variant refinement of tumor sequencing data

2018-02-16

Abstract excerpt

<h4>Purpose</h4> Manual review of aligned sequencing reads is required to develop a high-quality list of somatic variants from massively parallel sequencing data (MPS). Despite widespread use in analyzing MPS data, there has been little attempt to describe methods for manual review, resulting in high inter- and intra-lab variability in somatic variant detection and characterization of tumors. <h4>Methods</h4> Op...

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Literature Corpus work: 1846ae07-2452-53e5-8ee5-ca355d4e48b1
DOI: 10.1101/266262

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