Article

Synergistic Effects of HIF-1α Inhibition, Toll-Like Receptor 7 Agonist, and Chemotherapy in Mice Model of Colon Cancer

2022-06-09

Abstract excerpt

Recently, combination therapies have become a promising option with hopeful therapeutic outcomes due to their strong antitumor effects. Among them, despite the great success of cancer chemoimmunotherapy, it has not been able to improve the outcome of patients. Immunosuppressive tumor microenvironment (TME) has been recognized as the main barrier to immunotherapy. So, it has been assumed that targeting HIF-1α as a...

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Literature Corpus work: f975a754-6e63-5ed5-8904-54e0980d5311
DOI: 10.21203/rs.3.rs-1715706/v1

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