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Combination therapy of anti-TNF nanobody and PGE2 elevated therapeutic effect in experimental colits via regulating Treg/Th17 balance

2024-01-30

Abstract excerpt

Abstract Backgrounds and purpose: Anti-TNF therapy have gained great success in autoimmune disease. However, insufficient efficacy and safety of high dosage anti-TNF agents are exposed in amounts of clinical cases. Aiming at improving therapeutic of anti-TNF therapy, an anti-TNF nanobody V19 and combination therapy with PGE2 was introduced. Experimental Approach: DSS-induced colitis mice was used for evaluating th...

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Literature Corpus work
04fe0a28-d206-5d86-b553-1d065872606d
DOI
10.22541/au.170664485.50634661/v1
Open publication

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Combination therapy of anti-TNF nanobody and PGE2 elevated therapeutic effect in experimental colits via regulating Treg/Th17 balanceDOI 10.22541/au.170664485.50634661/v1
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