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Article

Circular RNA-OGDH promotes PANoptosis in diabetic cardiomyopathy: A novel mechanistic insight

22 May 2025

Abstract excerpt

Diabetic cardiomyopathy is a myocardial structural and functional abnormality directly caused by diabetes and is a principal factor in the development of cardiovascular complications in patients with diabetes. The study aims to investigate the role of circOGDH in the development of DCM and elucidate its precise underlying mechanisms. We established two well-characterized diabetic mouse models, C57BL/6J and db/db,...

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Share to Cardiovascular Disease and Adiposity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40412523
DOI: 10.1016/j.jbc.2025.110280

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