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The Cardiomyocyte Circadian Clock

4 Mar 2010

Abstract excerpt

Circadian misalignment has been implicated in the development of obesity, diabetes mellitus, and cardiovascular disease. Time-of-day-dependent synchronization of organisms with their environment is mediated by circadian clocks. This cell autonomous mechanism has been identified within all cardiovascular-relevant cell types, including cardiomyocytes. Recent molecular- and genetic-based studies suggest that the...

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PMID: 20203314
DOI: 10.1161/circresaha.109.209957

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