Article

Single-Cell and WGCNA Integrative Analysis Reveal the Key Chondrocytes Niches and Pathogenic Genes in Intervertebral Disc Degeneration

2025-03-14

Abstract excerpt

Intervertebral disc degeneration (IDD) is a leading cause of low back pain, necessitating a comprehensive understanding of the molecular mechanisms driving disc degeneration to develop effective preventive and therapeutic strategies. Chondrocytes, as the predominant cellular constituents of the nucleus pulposus, are thought to play a pivotal role in the pathogenesis of IDD. In this study, we leveraged publicly ava...

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Literature Corpus work: f8e99f4d-3586-5207-af71-838201110cd0
DOI: 10.1101/2025.03.07.642051

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