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A diagnostic signatures for intervertebral disc degeneration using TNFAIP6 and COL6A2 based on single-cell RNA-seq and bulk RNA-seq analyses

20 Dec 2024

Abstract excerpt

Objectives Intervertebral disc degeneration (IVDD) is a prevalent degenerative condition associated with a high incidence rate of low back pain and disability. This study aimed to identify potential biomarkers and signaling pathways associated with IVDD.Methods Biomarkers were discerned through bulk-RNA and single-cell RNA sequencing (scRNA-Seq) investigations of IVDD cases from the Gene Expression Omnibus (GEO)...

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Share to Cervical and Thoracic Myelopathy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39704340
DOI: 10.1080/07853890.2024.2443568

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