Identification of core genes in intervertebral disc degeneration using bioinformatics and machine learning algorithms

Abstract excerpt

Background: Intervertebral Disc Degeneration (IDD) is a major cause of lower back pain and a significant global health issue. However, the specific mechanisms of IDD remain unclear. This study aims to identify key genes and pathways associated with IDD using bioinformatics and machine learning algorithms. Methods: Gene expression profiles, including those from 35 LDH patients and 43 healthy volunteers, were...

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