Article

Single-cell transcriptome profiling reveals multicellular ecosystem of nucleus pulposus during degeneration progression

2021-05-26

Abstract excerpt

Degeneration of the nucleus pulposus (NP) is a major contributor to intervertebral disc degeneration (IVDD) and low back pain. However, the underlying molecular complexity and cellular heterogeneity remain poorly understood. Here, we first reported a comprehensive single-cell resolution transcriptional landscape of human NP. Six novel human nucleus pulposus cell (NPCs) populations were identified by distinct molec...

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Literature Corpus work: b9b75d7e-e8e0-5894-b168-74f85c15e69c
DOI: 10.1101/2021.05.25.445620

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