Article

Convergent Transcription of Interferon-Stimulated Genes by TNF-A and IFN-A Augments Antiviral Activity against HCV and HEV

2016-01-01

Abstract excerpt

IFN- has been used for decades to treat chronic hepatitis B and C, and as an off-label treatment for some cases of hepatitis E virus (HEV) infection. TNF- is another important cytokine involved in inflammatory disease, which can interact with interferon signaling. Because interferon-stimulated genes (ISGs) are the ultimate antiviral effectors of the interferon signaling, this study aimed to understand the regulati...

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Literature Corpus work: f8dbcbad-367e-568c-9c01-30260fb0f2ef
DOI: 10.1016/s0168-8278(16)00687-5

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