Article
Inhibition of ACSL4 ameliorates tubular ferroptotic cell death and protects against fibrotic kidney disease
2023-01-05
Abstract excerpt
<title>Abstract</title> <p>Ferroptosis is a recently recognized form of regulated cell death, characterized by iron-dependent accumulation of lipid peroxidation. Ample evidence has depicted that ferroptosis plays an essential role in the cause or consequence of human diseases, including cancer, neurodegenerative disease and acute kidney injury. However, the exact role and underlying mechanism of ferroptosis in fi...
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Identifiers and source
- Literature Corpus work
- f8d10d7e-aa72-56c8-b16b-9c75fe71552e
- DOI
- 10.21203/rs.3.rs-2379976/v1