Ferroptosis and renal fibrosis: A new target for the future (Review)

Abstract excerpt

Ferroptosis is a type of non-apoptotic controlled cell death triggered by oxidative stress and iron-dependent lipid peroxidation. Ferroptosis is regulated by signalling pathways that are associated with metabolism, including glutathione peroxidase 4 dysfunction, the cystine/glutamate antiporter system, lipid peroxidation and inadequate iron metabolism. Ferroptosis is associated with renal fibrosis; however,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biomarkers in Disease Mechanisms
• Share to Cancer, Lipids, and Metabolism
• Share to Ferroptosis and cancer prognosis