Article
Kidney tubular epithelial cell ferroptosis links glomerular injury to tubulointerstitial pathology in lupus nephritis
2022-09-23
Abstract excerpt
<title>Abstract</title> <p>While the deposition of immune complexes in the glomeruli is thought to initiate lupus nephritis, the extent of tubular damage better predicts progression to end stage kidney disease than the glomerular injury. However, the mechanisms underlying tubular injury in lupus nephritis are incompletely understood. Iron accumulates in tubular epithelial cells of lupus nephritis patients and mic...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- a2a84a01-a0d9-5e50-b5d3-fab908c64c76
- DOI
- 10.21203/rs.3.rs-2038767/v1