Article
Sex-specific Expression of Estradiol Derivatives, Hydropersulfides and Ether Lipids Regulates Ferroptosis Sensitivity of Kidney Tubules
2023-11-15
Abstract excerpt
<title>Abstract</title> <p>Acute kidney tubular necrosis (ATN) mediates acute kidney injury (AKI) and nephron loss, the major risk factor for chronic kidney disease (CKD) progression and end-stage renal disease (ESRD)<sup>1-3</sup>. For decades, it has been known that female tissue is less sensitive to AKI<sup>4,5</sup>, but the underlying mechanisms have remained elusive. As a specific feature, ATN is characteri...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- f82bb84b-8944-53cf-8b9d-489ed71e4d8a
- DOI
- 10.21203/rs.3.rs-3601108/v1