Article

Cross-Pipeline RNA-seq Analysis Reveals Core Regulatory Gene Signatures Driving P19 Cell Neurogenesis

2026-05-13

Abstract excerpt

I. Understanding the mechanisms governing neuronal differentiation is essential for elucidating neurodevelopmental processes and identifying therapeutic targets for neurological disorders. In this study, we optimized serum-dependent induction conditions and benchmarked multiple RNA-seq pipelines to establish a robust in-vitro model of neurogenesis using P19 embryonal carcinoma cells. Retinoic acid (RA, 0.5 µM) was...

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Literature Corpus work: f8c34198-90a2-5f86-b7f9-674561768dbb
DOI: 10.64898/2026.05.12.724245

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