Article

Time series scRNAseq analysis in mouse and human informs optimization of rapid astrocyte differentiation protocols

2021-12-09

Abstract excerpt

Macroglia (astrocytes and oligodendrocytes) are required for normal development and function of the central nervous system, yet many questions remain about their emergence in the brain and spinal cord. Here we used single-cell RNA sequencing (scRNAseq) to analyze over 298,000 cells and nuclei during macroglia differentiation from mouse embryonic and human induced pluripotent stem cells. We computationally identify...

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Literature Corpus work: 68e01ce7-a21b-5705-a494-4266a505e43c
DOI: 10.1101/2021.12.07.471509

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