Article

Single-Cell Transcriptomics of Glioblastoma Reveals Pericytes Contributing to Blood–Brain Tumor Barrier and Tumor Progression

2023-11-09

Abstract excerpt

<h4>Background: </h4> Pericytes compose blood–brain barrier (BBB) and may affects the blood-brain tumor barrier function (BBTB) in glioblastoma (GBM), which eventually affect chemotherapy efficiency and tumor progression of the disease. However, the expression signatures and detailed effect of these pericyte are still unclear. We aimed to identify these pericytes affecting BBTB in GBM, and to explore their clinica...

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Literature Corpus work: f8baf2ed-71fd-5a79-bc36-5201cbe63a99
DOI: 10.21203/rs.3.rs-3561475/v1

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