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Identification and Analysis of Glioblastoma Biomarkers Based on Single Cell Sequencing

4 Mar 2020

Abstract excerpt

Glioblastoma (GBM) is one of the most common and aggressive primary adult brain tumors. Tumor heterogeneity poses a great challenge to the treatment of GBM, which is determined by both heterogeneous GBM cells and a complex tumor microenvironment. Single-cell RNA sequencing (scRNA-seq) enables the transcriptomes of great deal of individual cells to be assayed in an unbiased manner and has been applied in head and...

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PMID: 32195242
DOI: 10.3389/fbioe.2020.00167

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