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Article

Upregulated functional gene expression programmes in tumour pericytes mark progression in patients with low‐grade glioma

21 May 2021

Abstract excerpt

Pericytes conceivably play important roles in the tumour microenvironment of glioblastoma multiforme (GBM) by allowing for an aberrant vasculature and acting as a component in the perivascular niche that supports glioma stem-like cells. However, a lack of specific markers has hampered in-depth elucidation of the functional contribution of pericytes to GBM. This study provides a comprehensive computational biology...

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PMID: 34018679
DOI: 10.1002/1878-0261.13016

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