Article

Evolution of transposable element-derived enhancer activity

2022-03-17

Abstract excerpt

Many transposable elements (TEs) contain transcription factor binding sites and are implicated as potential regulatory elements. However, TEs are rarely functionally tested for regulatory activity, which in turn limits our understanding of how TE regulatory activity has evolved. We systematically tested the human LTR18A subfamily for regulatory activity using massively parallel reporter assay (MPRA) and found AP-1...

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Literature Corpus work: 7c761f93-767d-52ec-801f-cb452cfc4451
DOI: 10.1101/2022.03.16.483999

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