Article

Transposable elements mediate genetic effects altering the expression of nearby genes in colorectal cancer

2021-12-17

Abstract excerpt

<title>Abstract</title> <p>Transposable elements (TEs) are interspersed repeats that contribute to more than half of the human genome, and TE-embedded regulatory sequences are increasingly recognized as major components of the human regulome. Perturbations of this system can contribute to tumorigenesis, but the impact of TEs on gene expression in cancer cells remains to be fully assessed. Here, we analyzed 275 no...

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Literature Corpus work: 6355dacc-423f-5337-b2b3-e0fa3f20c988
DOI: 10.21203/rs.3.rs-1138340/v1

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