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Article

Transposable elements in cancer and other human diseases.

Current cancer drug targets - 1 Jan 2015

Chenais Benoit

Abstract excerpt

Transposable elements (TEs) are mobile DNA sequences representing a substantial fraction of most genomes. Through the creation of new genes and functions, TEs are important elements of genome plasticity and evolution. However TE insertion in human genomes may be the cause of genetic dysfunction and alteration of gene expression contributing to cancer and other human diseases. Besides the chromosome rearrangements...

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PMID: 25808076
DOI: 10.2174/1568009615666150317122506

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