Article

Nuclear compartmentalization of TERT mRNA and TUG1 lncRNA transcripts is driven by intron retention: implications for RNA-directed therapies

2020-07-22

Abstract excerpt

Numerous global connections have been made between splicing and other layers of gene regulation, including the spatial partitioning of the transcriptome in the cell. Yet, there has been surprisingly little analysis of the spatio-temporal regulation of individual protein-coding and non-coding RNA molecules in single cells. Here we address how intron retention influences the spatio-temporal dynamics of transcripts f...

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Literature Corpus work: f82ebc5c-01ac-5047-b7e9-f1b622d4046c
DOI: 10.1101/2020.07.21.212514

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