Article
Nonsynonymous Single-Nucleotide Variations on Some Posttranslational Modifications of Human Proteins and the Association with Diseases.
Computational and mathematical methods in medicine - 1 Jan 2015
Sun Bo, Zhang Menghuan, Cui Peng, Li Hong, Jia Jia, Li Yixue, Xie Lu
Abstract excerpt
Protein posttranslational modifications (PTMs) play key roles in a variety of protein activities and cellular processes. Different PTMs show distinct impacts on protein functions, and normal protein activities are consequences of all kinds of PTMs working together. With the development of high throughput technologies such as tandem mass spectrometry (MS/MS) and next generation sequencing, more and more...
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