Article

Caspase-4 promotes both metastasis and interferon-γ-induced cell death in non-small cell lung cancer

2023-10-10

Abstract excerpt

<title>Abstract</title> <p>Caspase-4 (CASP4) is a member of the inflammatory caspase subfamily and promotes inflammation. Here, we report that CASP4 in non-small cell lung cancer cells contributes to both tumor progression via angiogenesis and tumor hyperkinesis and tumor cell killing in response to high interferon (IFN)-γ levels. We revealed that elevated CASP4 expression within the primary tumor was associated...

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Literature Corpus work: f7dc0afe-cadd-56c0-b10c-d340fe250d6f
DOI: 10.21203/rs.3.rs-3316572/v1

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