Article

Irradiation suppresses STAT3-mediated MCL1 expression to augment CD8+ T cells cytotoxicity against EGFR-positive lung cancer

2021-05-11

Abstract excerpt

<title>Abstract</title> Background Tumor cells progress to evade immunological attacks and prohibit activity of CD8+ T cells. Irradiation damages tumor cells and augments tumor immunotherapy in clinical application. However, the detail mechanism remains elusive. We aimed to uncover the mechanism of irradiation augmenting cytotoxic CD8+ T cells to suppress tumor progression in non-small-c...

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Literature Corpus work: e1a624a1-c5c5-5e0f-aeb0-5899f32445f9
DOI: 10.21203/rs.3.rs-497648/v1

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