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TM4SF1 Promotes Proliferation, Invasion, and Metastasis in Human Liver Cancer Cells

3 May 2016

Abstract excerpt

Transmembrane 4 superfamily member 1 (TM4SF1) is a member of tetraspanin family, which mediates signal transduction events regulating cell development, activation, growth and motility. Our previous studies showed that TM4SF1 is highly expressed in liver cancer. HepG2 cells were transfected with TM4SFl siRNA and TM4SF1-expressing plasmids and their biological functions were analyzed in vitro and in vivo. HepG2...

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PMID: 27153056
DOI: 10.3390/ijms17050661

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