Article

Palbociclib induces the apoptosis of lung squamous cell carcinoma cells via Rb-independent STAT3 phosphorylation

2022-06-14

Abstract excerpt

<title>Abstract</title> <p>Lung squamous cell carcinoma (LUSC) treatment response is poor and treatment alternatives are limited. Palbociclib, a cyclin-dependent kinase (CDK) 4/6 inhibitor, has recently been approved for hormone receptor-positive breast cancer patients and applied in multiple preclinical models, but its use for LUSC therapy remains elusive. Here, we investigated whether palbociclib induced cell a...

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Literature Corpus work: f9978c3b-3af0-5a8e-b563-c7ecf70a6901
DOI: 10.21203/rs.3.rs-1733404/v1

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