Article

Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery

2022-05-27

Abstract excerpt

<h4>ABSTRACT</h4> Uneven worldwide vaccination coverage against SARS-CoV-2 and emergence of variants escaping immunity call for broadly-effective and easily-deployable therapeutics. We previously described the human single-chain scFv76 antibody, which recognizes SARS-CoV-2 Alfa, Beta, Gamma and Delta variants. We now show that scFv76 also neutralizes infectivity and fusogenic activity of Omicron BA.1 and BA.2 var...

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Literature Corpus work: f7ce8543-02ec-5d3e-97ad-79b7749b2dd3
DOI: 10.1101/2022.05.27.493569

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