Article

Intranasal inhibitor broadly blocks SARS-CoV-2 including recent highly immunoevasive Omicron subvariants

2021-12-28

Abstract excerpt

<h4>SUMMARY</h4> The recent emergence of novel SARS-CoV-2 variants capable of efficiently escaping neutralizing antibodies emphasizes the need for prophylactic strategies to complement vaccination in fighting the COVID-19 pandemic. Nasal epithelium is rich in the ACE2 receptor and important for SARS-CoV-2 transmission by supporting early viral replication before seeding to the lung 1 . Intranasal administration...

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Literature Corpus work: 198145ed-0440-5986-8e9d-128aa070728b
DOI: 10.1101/2021.12.28.474326

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