Article

Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains

2022-03-18

Abstract excerpt

<h4>ABSTRACT</h4> Omicron variant strains encode large numbers of changes in the spike protein compared to historical SARS-CoV-2 isolates. Although in vitro studies have suggested that several monoclonal antibody therapies lose neutralizing activity against Omicron variants 1-4 , the effects in vivo remain largely unknown. Here, we report on the protective efficacy against three SARS-CoV-2 Omicron lineage stra...

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Literature Corpus work: 904f1f0e-65af-542f-ac53-cd59d058a325
DOI: 10.1101/2022.03.17.484787

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