Article

A potent bispecific nanobody protects hACE2 mice against SARS-CoV-2 infection via intranasal administration

2021-02-09

Abstract excerpt

The dramatically expanding COVID-19 needs multiple effective countermeasures. Neutralizing antibodies are a potential therapeutic strategy for treating COVID-19. A number of neutralizing nanobodies (Nbs) were reported for their in vitro activities. However, in vivo protection of these nanobodies was not reported in animal models. In the current report, we characterized several RBD-specific Nbs isolated from a sc...

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Literature Corpus work: 9b6d64e6-ea28-589f-9509-d58e8c3bb5f7
DOI: 10.1101/2021.02.08.429275

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