Article

Shallow whole genome sequencing for robust copy number profiling of formalin-fixed paraffin-embedded breast cancers

2017-12-08

Abstract excerpt

<h4>ABSTRACT</h4> Pathology archives with linked clinical data are an invaluable resource for translational research, with the limitation that most cancer samples are formalin-fixed paraffin-embedded (FFPE) tissues. Therefore, FFPE tissues are an important resource for genomic profiling studies but are under-utilised due to the low amount and quality of extracted nucleic acids. We profiled the copy number landsca...

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Literature Corpus work: f7a955f7-84ba-5948-b249-0298b634d792
DOI: 10.1101/231480

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