Article

AMPK regulates small RNA pathway prevalence to mediate soma-to-germ line communication and establish germline stem cell quiescence

2023-11-15

Abstract excerpt

It is well established that cells communicate with each other via signaling molecules and pathways. Recent work has further indicated that this transfer of information can breach the soma-to-germ line barrier, thus permitting changes in germline gene expression in response to cellular decisions made in somatic lineages. We show that during periods of extended energy stress AMPK alters small RNA biogenesis in somat...

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Literature Corpus work: f7a797af-4edd-52a6-a0f9-2d81bd460836
DOI: 10.1101/2023.11.15.567172

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